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Article in the Journal of AIDS and HIV Research Vol. 3(5), pp. 100-102, May 2011. A better understanding of the significance and determinants of loss of follow-up and key potential related outcome measures, such as death and missed study visit would assist program evaluation and provide basis for future interventions. Senegal has one of Africa’s lowest HIV/AIDS infection rate, less than 1%. But vulnerable groups such as sex workers have higher HIV prevalence. Currently, HIV infection among legal sex workers in Dakar has risen to 27.1%, compared to 1% 20 years ago, (Fact sheet, 2004). The prostitution in Senegal has