Paulo Longo Research Initiative

Let’s dive right in. Addyi, also known by its chemical name flibanserin, is a prescription pill for women dealing with something many struggle to talk about—low libido. Specifically, it’s for women who are premenopausal and experiencing Hypoactive Sexual Desire Disorder (HSDD). Imagine constantly feeling disconnected from your own desire, no matter how hard you try. That’s what Addyi aims to help with. Now, I know what you’re thinking—”Isn’t this just like Viagra for women?” Well, not quite. While Viagra works physically by increasing blood flow for men, Addyi works on the brain, targeting neurotransmitters to help restore balance. Think of it as giving your libido a little nudge from the inside out. How Does Addyi Work (Spoiler: Not Instantly) When we say Addyi works on the brain, we mean it adjusts the levels of chemicals like dopamine and serotonin. These two are pretty much the “Yin and Yang” of desire—dopamine revs up your interest, while serotonin can sometimes hit the brakes. What Addyi does is shift that balance so you get more of the excitement and less of the indifference. The pill needs to be taken daily, and you’ll likely start seeing results after 4-8 weeks of sticking with it.

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When Is Tenofovir Used? Tenofovir is the trade name of the medicine Tenofovir disoproxil, a synthetic antiviral drug that is pharmacologically classified as a nucleoside reverse transcriptase inhibitor. This drug was synthesized in the Czech Republic in the mid-1980s, and in 1997, American scientists proved the effectiveness of Tenofovir against HIV in humans. Tenofovir was originally administered subcutaneously and later became available for oral administration. In addition to treating HIV infection, Tenofovir is also used in the treatment of chronic viral hepatitis B. The FDA approved Tenofovir for the treatment of HIV in 2001 and for the treatment of hepatitis B in 2008. To date, Tenofovir is available in tablets for oral administration at a dosage of 300 mg of the active ingredient in one tablet. Tablets are film-coated light blue in color, they are oval, biconvex, on the cross section they have a white or almost white, slightly yellowish color. Excipients (magnesium stearate, pregelatinized starch, microcrystalline cellulose, lactose monohydrate and croscarmellose sodium), as well as a number of dyes and fixatives that form a film coating, don’t affect the effect of the drug. When Is Tenofovir Contraindicated? The main contraindication to the use of Tenofovir is hypersensitivity to this

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